Synovial Fluid as a Lubricant

A model of synovial fluid lubricant composition in normal and injured joints.

The synovial fluid (SF) of joints normally functions as a biological lubricant, providing low-friction and low-wear properties to articulating cartilage surfaces through the putative contributions of proteoglycan 4 (PRG4), hyaluronic acid (HA), and surface active phospholipids (SAPL). These lubricants are secreted by chondrocytes in articular cartilage and synoviocytes in synovium, and concentr...

Does intra-articular fracture change the lubricant content of synovial fluid?

BACKGROUND Lubrication function is impaired and the lubricant content of synovial fluid (SF) changes immediately after plateau tibia fractures. Here, we aimed to analyze the lubricant content of SF at chronic term following plateau tibia fracture. METHODS Forty-eight surgically treated patients without joint incongruency (<2 mm displacement) were included in the study. Joint aspiration had be...

Synovial perfusion and synovial fluid solutes.

answer goes back to the cardinal signs of inflammation. The redness and heat of this state relate directly to increased local blood supply, and these critical findings cannot be examined systematically without accurate quantification of flow. Further, the imbalances of vascular permeability and tissue clearance that lead to tissue swelling cannot be evaluated usefully without an understanding o...

Synovial Fluid Mucin.

Synovial mucin, the characteristic component of synovial fluid, was first isolated in 1846 by Frerichs (1846), who precipitated it from joint fluid by addition of. acetic acid. Its high viscosity and peculiar chemical composition made it a subject of much interest. Frerichs realized that it was a complex of protein and carbohydrate components, but little -additional information was added until ...

Elasticity of synovial fluid.